Q:
In support of an editorial comment I’m working on with a colleague, I just read your paper: The real cost of sequencing: higher than you think!

It is right on the money…as far as the topic I’m interested in but is, obviously, dated (but was helpful for me nonetheless). Pubmed didn’t bring up a more recent revision of your paper…so I assume it hasn’t been updated.

Can you recommend any other, more recent papers or resources that address the issue of cost/price of sequencing? The NHGRI webpage on this topic is also helpful, but it was written in 2016 and does not address the post sequencing costs such as variant calling, annotation, and interpretation. Do you think your illustration of the proportion of costs in 2020 due to the different components of testing still holds true?

A:
see
http://papers.gersteinlab.org/papers/costseq2
http://papers.gersteinlab.org/papers/dsg